Contraindicated Substances for G6PD Deficient Patients

Avoid moth balls, blue food color, legumes (fava beans, beans, peas, peanuts, soy, lentils, etc.), sulfites, tonic water. Please read all labels on processed foods before feeding to patient.

Substances labeled Low Risk MAY be given safely at normal therapeutic doses UNLESS the patient is severely G6PD Deficient or has chronic non-spherocytic hemolytic anemia. There is no guarantee that low risk drugs will not cause hemolysis. Please see http://g6pddeficiency.org/index.php for more information.

A diet rich in antioxidant foods is recommended to help minimize the effects of oxidative stress and the resultant hemolysis.

Acetaminophen - Low Risk Pamaquine - High Risk
Acetanilid - High Risk Para-Aminobenzoic Acid - Low Risk
Acetylphenylhydrazine - High Risk Pefloxacin - High Risk
Aminophenazone - Low Risk Pentaquine - High Risk
Antazoline - Low Risk Phenacetin - High Risk
Antipyrine - Low Risk Phenazopyridine - High Risk
Ascorbic Acid - Low Risk Phenylbutazone - Low Risk
Aspirin - High Risk Phenylhydrazine - High Risk
Astemizole - Risk Phenytoin - Low Risk
Beta-Naphthol - High Risk Primaquine - High Risk
Chloramphenicol - High Risk Probenecid - High Risk
Chloroquine - High Risk Procainamide - Low Risk
Ciprofloxacin - High Risk Proguanil - Low Risk
Colchicine - Low Risk Pyrimethamine - Low Risk
Dapsone - High Risk Quinacrine - High Risk
Dimercaprol - High Risk Quinidine - Low Risk
Diphenhydramine - Low Risk Quinine - Low Risk
Dopamine - Low Risk Stibophen - High Risk
Doxorubicin - High Risk Streptomycin - Low Risk
Furazolidone - High Risk Sulfacetamide - High Risk
Glucosulfone - High Risk Sulfacytine - Low Risk
Glyburide - High Risk Sulfadiazine - Low Risk
Henna - High Risk Sulfadimidine - High Risk
Ibuprofen - Low Risk Sulfafurazole - High Risk
Isobutyl Nitrite - High Risk Sulfaguanidine - Low Risk
Isoniazid - Low Risk Sulfamerazine - Low Risk
Lamotrigine - High Risk Sulfamethoxazole - High Risk
Levofloxacin - High Risk Sulfamethoxypyridazine - Low Risk
Menadiol Sodium Sulfate (Vitamin k4 sodium sulfate) - High Risk Sulfanilamide - High Risk
Menadione - High Risk Sulfapyridine - High Risk
Menadione sodium Bisulfite (Vitamin K3 sodium bisulfite) - High Risk Sulfasalazine - High Risk
Menthol - High Risk Sulfathiazole - High Risk
Mesalazine - High Risk Sulfonylurea - Low Risk
Methylene Blue - High Risk Sulfoxone - High Risk
Mirtazapine - Low Risk Tamsulosin - High Risk
Moxifloxacin - High Risk Tiaprofenic Acid - Low Risk
Nalidixic Acid - High Risk Toluidine Blue - High Risk
Naphthalene - High Risk Trihexyphenidyl - Low Risk
Niridazole - High Risk Trimethoprim - Low Risk
Nitrofurantoin - High Risk Trinitrotoluene - High Risk
Nitrofurazone - High Risk Tripelennamine - Low Risk
Norfloxacin - Low Risk Vitamin K1 - Low Risk
Oxidase, Urate - High Risk